| Importance of TP53 codon 72 and intron 3 duplication 16bp ...
The purpose of this study was to evaluate the role of Arg72Pro and PIN3 Ins16bp polymorphisms in TP53 gene as genetic susceptibility and predictive markers to breast cancer. Methods We analysed DNA samples from 264 breast cancer patients and 440 controls, for TP53 Arg72Pro and PIN3 Ins16bp polymorphisms using PCR-RFLP. Results We observed that women with A2A2 genotype have increased risk for developing breast cancer, either in women with or without familial history (FH) of the disease (OR=4.40, 95% CI 1.60-12.0; p=0.004; OR=3.88, 95% CI 1.18-12.8; p=0.026, respectively). In haplotype analysis, statistically significant differences were found betweenTP53 Arg-A2 haplotype frequencies and familial breast cancer cases and the respective control group (OR=2.10, 95% CI 1.08-4.06; p=0.028).
Kidney cancer drug attacks a major type of acute myeloid leukemia
A drug used to treat kidney cancer also targets a genetic mutation active in about one third of patients with acute myeloid leukemia (AML), the most common and lethal form of adult leukemia, researchers at The University of Texas M. D. Anderson Cancer Center report in the Jan. 29 edition of the Journal of the National Cancer Institute. .
Hip-Hop Rumors: Angel Lola Luv’s Implants EXPOSED! Jim Jones Vs. Max ...
Diddy wants another assistant and he is using the internet to find his candidate – kinda. I don't know what happened to the first round of youtube boobs, but he is at it again. Stay tuned for the rumor below. First, peep the site WorkForPdiddy.com (is he going back to P.Diddy?). Also, click here for further details.
Here is the rumor. I heard that Diddy is going to be taping at all this open calls and it is all going to be turned in to a television series like American Idol or something. I don't think I can hold an umbrella long enough to be Diddy's assistant.
CHUCK D ADDRESSES THE DEF JAM RUMORS
There have been Def Jam rumors swirling around for some time as to who will replace Jay-Z as the president of the label.
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